作者
Rehan J Haidry, Jason M Dunn, Mohammed A Butt, Matthew G Burnell, Abhinav Gupta, Sarah Green, Haroon Miah, Howard L Smart, Pradeep Bhandari, Lesley Ann Smith, Robert Willert, Grant Fullarton, John Morris, Massimo Di Pietro, Charles Gordon, Ian Penman, Hugh Barr, Praful Patel, Philip Boger, Neel Kapoor, Brinder Mahon, Jonathon Hoare, Ravi Narayanasamy, Dermot O'Toole, Edward Cheong, Natalie C Direkze, Yeng Ang, Marco Novelli, Matthew R Banks, Laurence Bruce Lovat
发表日期
2013/7/1
期刊
Gastroenterology
卷号
145
期号
1
页码范围
87-95
出版商
WB Saunders
简介
BACKGROUND & AIMS
Patients with Barrett's esophagus (BE) and high-grade dysplasia (HGD) or early neoplasia increasingly receive endoscopic mucosal resection and radiofrequency ablation (RFA) therapy. We analyzed data from a UK registry that follows the outcomes of patients with BE who have undergone RFA for neoplasia.
METHODS
We collected data on 335 patients with BE and neoplasia (72% with HGD, 24% with intramucosal cancer, 4% with low-grade dysplasia [mean age, 69 years; 81% male]), treated at 19 centers in the United Kingdom from July 2008 through August 2012. Mean length of BE segments was 5.8 cm (range, 1−20 cm). Patients' nodules were removed by endoscopic mucosal resection, and the patients then underwent RFA every 3 months until all areas of BE were ablated or cancer developed. Biopsies were collected 12 months after the first RFA; clearance of HGD, dysplasia, and …
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RJ Haidry, JM Dunn, MA Butt, MG Burnell, A Gupta… - Gastroenterology, 2013