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Species in the genus Aspergillus are saprophytic filamentous fungi that are most commonly found in soil and litter environments of subtropical and warm temperate latitudes [1]. Inhalation of asexual spores produced by Aspergillus fumigatus and a few other species in the genus cause a group of diseases collectively referred to as aspergillosis [2]. The most severe form of aspergillosis is invasive aspergillosis, which primarily affects individuals with compromised immune systems or preexisting lung conditions [3]. Since drugs targeting invasive aspergillosis are not always effective due to our lack of understanding of how they function inside the human host [4] and the evolution of drug resistance [5, 6], infected individuals suffer high morbidity and mortality [7]. Collectively, Aspergillus fungi affect millions of patients and cause hundreds of thousands of life-threatening infections every year [8, 9]. Not all pathogenic Aspergillus species exhibit the same infection rates [10, 11]. Approximately 70% of all Aspergillus infections are caused by A. fumigatus, whereas the remaining 30% of infections stem from other species in the genus [12]. Some of these other pathogenic species–for example, Aspergillus flavus, Aspergillus niger, and Aspergillus terreus–are distantly related to A. fumigatus [12]; each of these three species belong to different Aspergillus sections (note “section” is a taxonomic rank in-between the genus and species ranks) and show extensive genomic divergence [13]. However, there are also pathogenic Aspergillus species, such as Aspergillus lentulus and Aspergillus udagawae, that belong to the same section as A. fumigatus (section Fumigati …