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Breast cancer, being the most prevalent cancer among women worldwide, leads to about 400,000 deaths yearly. All women should have a basic understanding of breast self-examination (BSE). This study aims at determining university students’ knowledge, behavior and beliefs about breast cancer and BSE. Data were obtained using a structured questionnaire that was distributed over 1200 female university students in 6 Palestinian universities. The questionnaire evaluated the students’ knowledge, behavior, and attitudes about breast cancer and BSE. The study revealed that 86% of the participants had an awareness of breast cancer and 33% were aware of the term BSE. Only 45% of the participants had ever performed BSE. The study also revealed some misconceptions related to breast cancer; about half of the participants believed that breast cancer certainly leads to death and 24% of them believed that a …