作者
K‐H Yiu, C‐K Yeung, C‐T Zhao, JC Chan, C‐W Siu, S Tam, C‐S Wong, GH Yan, WS Yue, P‐L Khong, HH Chan, H‐F Tse
发表日期
2013/3
期刊
Journal of internal medicine
卷号
273
期号
3
页码范围
273-282
简介
Objective
Patients with psoriasis are prone to premature atherosclerosis and increased risk of cardiovascular disease events. However, the prevalence and extent of atherosclerosis in patients with psoriasis are unknown.
Design
A cross‐sectional study.
Setting and subjects
The prevalence and extent of coronary and carotid atherosclerosis were compared in 70 patients with psoriasis (46 ± 9 years, 71% male) without known cardiovascular disease or joint involvement and 51 age‐ and gender‐matched healthy control subjects (45 ± 7 years, 71% male). Systemic inflammation was assessed by the level of high‐sensitivity C‐reactive protein (hs‐CRP). Coronary atherosclerosis was determined by the coronary calcification score (CCS) measured by multi‐detector computed tomography. Carotid atherosclerosis was assessed by high‐resolution ultrasound‐derived carotid intima–media thickness (cIMT).
Results …
引用总数
201220132014201520162017201820192020202120222023202417111311866791132
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KH Yiu, CK Yeung, CT Zhao, JC Chan, CW Siu, S Tam… - Journal of internal medicine, 2013