作者
Yue Xiao, Yingxuan Feng, Jianxin Zhao, Wei Chen, Wenwei Lu
发表日期
2024/3/9
来源
Journal of Advanced Research
出版商
Elsevier
简介
Background
Population aging has become a primary global public health issue, and the prevention of age-associated diseases and prolonging healthy life expectancies are of particular importance. Gut microbiota has emerged as a novel target in various host physiological disorders including aging. Comprehensive understanding on changes of gut microbiota during aging, in particular gut microbiota characteristics of centenarians, can provide us possibility to achieving healthy aging or intervene pathological aging through gut microbiota-directed strategies.
Aim of Review
This review aims to summarize the characteristics of the gut microbiota associated with aging, explore potential biomarkers of aging and address microbiota-associated mechanisms of host aging focusing on intestinal barrier and immune status. By summarizing the existing effective dietary strategies in aging interventions, the probability of …
学术搜索中的文章
Y Xiao, Y Feng, J Zhao, W Chen, W Lu - Journal of Advanced Research, 2024