作者
Anurag Mehta, Joseph Rigdon, Matthew C Tattersall, Charles A German, Thomas A Barringer III, Parag H Joshi, Laurence S Sperling, Matthew J Budoff, Alain Bertoni, Erin D Michos, Michael J Blaha, James H Stein, Michael D Shapiro
发表日期
2021/4
期刊
Circulation: Cardiovascular Imaging
卷号
14
期号
4
页码范围
e011701
出版商
Lippincott Williams & Wilkins
简介
Background
Absence of coronary artery calcium (CAC) identifies asymptomatic individuals at low cardiovascular disease risk. Carotid artery plaque is a marker of increased risk, but its association with cardiovascular risk and incident CAC in people without CAC is unclear.
Methods
Multi-Ethnic Study of Atherosclerosis participants with CAC score of 0 at enrollment who also underwent carotid plaque measurement using B-mode ultrasonography were prospectively followed for incident coronary heart disease, stroke, and cardiovascular disease events, and CAC (score >0 on up to 3 serial computed tomography scans). The association of carotid plaque presence and plaque score (Ln[score+1]) at baseline with cardiovascular events and incident CAC was evaluated with Cox proportional hazards regression models adjusted for demographics, risk factors, and statin use.
Results
Among these 2673 participants (58 …
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A Mehta, J Rigdon, MC Tattersall, CA German… - Circulation: Cardiovascular Imaging, 2021