作者
Fever and Antipyretic in Critically ill patients Evaluation (FACE) Study Group, Byung Ho Lee, Daisuke Inui, Gee Young Suh, Jae Yeol Kim, Jae Young Kwon, Jisook Park, Keiichi Tada, Keiji Tanaka, Kenichi Ietsugu, Kenji Uehara, Kentaro Dote, Kimitaka Tajimi, Kiyoshi Morita, Koichi Matsuo, Koji Hoshino, Koji Hosokawa, Kook Hyun Lee, Kyoung Min Lee, Makoto Takatori, Masaji Nishimura, Masamitsu Sanui, Masanori Ito, Moritoki Egi, Naofumi Honda, Naoko Okayama, Nobuaki Shime, Ryosuke Tsuruta, Satoshi Nogami, Seok-Hwa Yoon, Shigeki Fujitani, Shin Ok Koh, Shinhiro Takeda, Shinsuke Saito, Sung Jin Hong, Takeshi Yamamoto, Takeshi Yokoyama, Takuhiro Yamaguchi, Tomoki Nishiyama, Toshiko Igarashi, Yasuyuki Kakihana, Younsuck Koh
发表日期
2012/2
期刊
Critical care
卷号
16
页码范围
1-13
出版商
BioMed Central
简介
Introduction
Fever is frequently observed in critically ill patients. An independent association of fever with increased mortality has been observed in non-neurological critically ill patients with mixed febrile etiology. The association of fever and antipyretics with mortality, however, may be different between infective and non-infective illness.
Methods
We designed a prospective observational study to investigate the independent association of fever and the use of antipyretic treatments with mortality in critically ill patients with and without sepsis. We included 1,425 consecutive adult critically ill patients (without neurological injury) requiring > 48 hours intensive care admitted in 25 ICUs. We recorded four-hourly body temperature and all antipyretic treatments until ICU discharge or 28 days after ICU admission, whichever occurred first. For septic and non-septic …
学术搜索中的文章
Fever and Antipyretic in Critically ill patients Evaluation … - Critical care, 2012