作者
Sheila F Lumley, David W Eyre, Anna L McNaughton, Alison Howarth, Sarah Hoosdally, Stephanie B Hatch, James Kavanagh, Kevin K Chau, Louise O Downs, Stuart Cox, Laura Dunn, Anita Justice, Susan Wareing, Kate Dingle, Justine Rudkin, Kathryn Auckland, Alexander Fyfe, Jai Bolton, Robert Paton, Alexander J Mentzer, Katie Jeffery, Monique I Andersson, Tim James, Tim EA Peto, Brian D Marsden, Gavin Screaton, Richard J Cornall, Paul Klenerman, Daniel Ebner, David I Stuart, Derrick W Crook, Nicole Stoesser, Stephen H Kennedy, Craig Thompson, Sunetra Gupta, Philippa C Matthews
发表日期
2020/10/22
期刊
Eurosurveillance
卷号
25
期号
42
页码范围
2001721
出版商
European Centre for Disease Prevention and Control
简介
SARS-CoV-2 IgG screening of 1,000 antenatal serum samples in the Oxford area, United Kingdom, between 14 April and 15 June 2020, yielded a 5.3% seroprevalence, mirroring contemporaneous regional data. Among the 53 positive samples, 39 showed in vitro neutralisation activity, correlating with IgG titre (Pearson’s correlation p<0.0001). While SARS-CoV-2 seroprevalence in pregnancy cohorts could potentially inform population surveillance, clinical correlates of infection and immunity in pregnancy, and antenatal epidemiology evolution over time need further study.
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