查看文章

Coumarin is a benzopyranone derivative with potential activities. Coumarin is generally obtained from a natural source, and also can be chemically synthesized. Coumarins are abundant in nature, and their sources include plant root, rhizomes, leaves, bark, in addition to several marine plants. Simple coumarins are commonly observed in most of the flowering plants, mainly belonging to the families of Rutaceae, Apiaceae, Asteraceae, Lamiaceae, Clusiaceae, Thymelaeaceae, and Oleaceae. In nature, coumarins are of four major sub-types, namely the simple coumarins, pyranocoumarins, furanocoumarins, and the pyrone-substituted coumarins. Osthenol, a prenylated coumarin is a potent monoamine oxidase inhibitor. Coumarins exhibit antifungal, anti-inflammatory activity and antimicrobial activities. Panitins A–G, newer coumarin derivatives are observed with lipopolysaccharide-induced nitric oxide …