作者
Simone A Dijkland, Isabel RA Retel Helmrich, Daan Nieboer, Mathieu Van Der Jagt, Diederik WJ Dippel, David K Menon, Nino Stocchetti, Andrew IR Maas, Hester F Lingsma, Ewout W Steyerberg, CENTER-TBI participants and investigators
发表日期
2021/5/15
期刊
Journal of neurotrauma
卷号
38
期号
10
页码范围
1377-1388
出版商
Mary Ann Liebert, Inc., publishers
简介
The International Mission on Prognosis and Analysis of Clinical Trials in Traumatic Brain Injury (IMPACT) and Corticoid Randomisation After Significant Head injury (CRASH) prognostic models predict functional outcome after moderate and severe traumatic brain injury (TBI). We aimed to assess their performance in a contemporary cohort of patients across Europe. The Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) core study is a prospective, observational cohort study in patients presenting with TBI and an indication for brain computed tomography. The CENTER-TBI core cohort consists of 4509 TBI patients available for analyses from 59 centers in 18 countries across Europe and Israel. The IMPACT validation cohort included 1173 patients with GCS ≤12, age ≥14, and 6-month Glasgow Outcome Scale-Extended (GOSE) available. The CRASH validation …
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SA Dijkland, IRAR Helmrich, D Nieboer… - Journal of neurotrauma, 2021