作者
Xuan Zhang, Jun Xia, Ying Jiang, David S Pisetsky, Josef S Smolen, Rong Mu, Shengming Dai, Michael E Weinblatt, Tore K Kvien, Juan Li, Thomas Dörner, Yu Zhang, Liwei Lu, Chengde Yang, Pingting Yang, Yuan Zhang, Chenchen Xu, Zhan Zhao, Peter E Lipsky
发表日期
2024/1/1
期刊
Journal of Autoimmunity
卷号
142
页码范围
103148
出版商
Academic Press
简介
Background
Rheumatoid arthritis (RA) is a chronic autoimmune disorder that affects the joints and produces pain, swelling, and stiffness. It has a lifetime prevalence of up to 1% worldwide. An extract of Tripterygium wilfordii Hook F (TwHF), a member of the Celastraceae herbal family widely available in south China, has been used for treatment of RA since 1960s.
Methods
The current consensus practice guidance (CPG) aims to offer guidance on the application of TwHF in the clinical management of active RA. The CPG followed World Health Organisation (WHO)'s recommended process, carried out three systematic reviews to synthesize data from 19 randomised controlled trials (RCT) involving 1795 participants. We utilized Grading of Recommendations, Assessment, Development and Evaluation (GRADE) to evaluate certainty of evidence and derive recommendations. We rigorously followed The Appraisal of …
学术搜索中的文章
X Zhang, J Xia, Y Jiang, DS Pisetsky, JS Smolen, R Mu… - Journal of Autoimmunity, 2024