作者
Sukhpreet K Tamana, Lisa Smithson, Amanda Lau, Jennifer Mariasine, Rochelle Young, Joyce Chikuma, Diana L Lefebvre, Padmaja Subbarao, Allan B Becker, Stuart E Turvey, Malcolm R Sears, CHILD Study Investigators, Jacqueline Pei, Piush J Mandhane
发表日期
2018/1
期刊
Sleep
卷号
41
期号
1
页码范围
zsx177
出版商
Oxford University Press
简介
Study Objectives
To examine the association between the age of onset and duration of parent-reported symptoms of sleep-disordered breathing (SDB) and behavioral problems at age 2.
Methods
Parent-reported SDB symptoms were assessed quarterly between 3 months and 2 years among 583 Canadian Healthy Infant Longitudinal Development Edmonton-site participants. Parent-reported SDB symptoms were clustered into phenotypes using group-based trajectory analysis based on age of onset and duration of symptoms. Home-based polysomnography (PSG) was completed at 1 year. The Child Behavior Checklist preschool-version (Mean T-score 50, standard deviation 10 points) assessed total, externalizing (attention), and internalizing (anxiety, depression) behaviors at 2 years.
Results
Four phenotypes were identified: no SDB (64.7%), early-onset …
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SK Tamana, L Smithson, A Lau, J Mariasine, R Young… - Sleep, 2018