作者
Marielle Kloosterman, Winnie Chua, Larissa Fabritz, Hussein R Al-Khalidi, Ulrich Schotten, Jens C Nielsen, Jonathan P Piccini, Luigi Di Biase, Karl Georg Häusler, Derick Todd, Lluis Mont, Isabelle C Van Gelder, Paulus Kirchhof, AXAFA-AFNET 5 investigators
发表日期
2020/7/1
期刊
EP Europace
卷号
22
期号
7
页码范围
1026-1035
出版商
Oxford University Press
简介
Aims
Study sex-differences in efficacy and safety of atrial fibrillation (AF) ablation.
Methods and results
We assessed first AF ablation outcomes on continuous anticoagulation in 633 patients [209 (33%) women and 424 (67%) men] in a pre-specified subgroup analysis of the AXAFA-AFNET 5 trial. We compared the primary outcome (death, stroke or transient ischaemic attack, or major bleeding) and secondary outcomes [change in quality of life (QoL) and cognitive function] 3 months after ablation. Women were older (66 vs. 63 years, P < 0.001), more often symptomatic, had lower QoL and a longer history of AF. No sex differences in ablation procedure were found. Women stayed in hospital longer than men (2.1 ± 2.3 vs. 1.6 ± 1.3 days, P = 0.004). The primary outcome occurred in 19 (9.1%) women and 26 (6.1%) men, P = 0.19. Women experienced more bleeding …
学术搜索中的文章
M Kloosterman, W Chua, L Fabritz, HR Al-Khalidi… - EP Europace, 2020