作者
Angelina Covita, Michael H Chen, Conor Leahy
发表日期
2019/7/22
期刊
Investigative ophthalmology & visual science
卷号
60
期号
9
页码范围
6793-6793
出版商
The Association for Research in Vision and Ophthalmology
简介
Purpose: Meibomian gland dysfunction (MGD), a significant component in dry eye disease, is characterized by blockage of meibomian gland ducts, thickening of gland contents, cysts, and the eventual disappearance of damaged glands. Tear breakup time (TBUT) is a clinical test used to assess evaporative dry eye disease. In this study, we aim to determine the correlation between meibomian gland dropout and TBUT.
Methods: In-house volunteers with self-described dry eye were recruited. After applying topical sodium fluorescein, a video image sequence (4 frames per second) of the ocular surface was recorded using a modified split-scanning ophthalmoscope CLARUS TM 500 (ZEISS, Dublin, CA). The device was configured with filters to isolate the dye fluorescence signal. Based on the recorded video, the TBUT was determined. The lower lids were everted and the meibomian glands were imaged with a …
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A Covita, MH Chen, C Leahy - Investigative ophthalmology & visual science, 2019