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Objectives: We examined whether resilience moderated the impact of stress on depressive symptoms in adolescent girls. Methods: Participants were 510 6th through 12th grade girls who completed a health survey. Hierarchical multiple regression examined the moderating effect of resilience on the relationship between stress and depressive symptoms. Results: There were sig- nificant main effects for stress (β = .51, p Conclusions: Adolescent girls with higher resilience appeared protected from the impact of stress on depressive symptoms.