作者
Jun Soo Jeong, Hyun Ki Kim, Cho-Rok Lee, Seulkee Park, Jae Hyun Park, Sang-Wook Kang, Jong Ju Jeong, Kee-Hyun Nam, Woong Youn Chung, Cheong Soo Park
发表日期
2012/8
期刊
Journal of Korean medical science
卷号
27
期号
8
页码范围
883
出版商
Korean Academy of Medical Sciences
简介
The study aimed to identify the clinical characteristics of coexisting chronic lymphocytic thyroiditis (CLT) in papillary thyroid carcinoma (PTC) and to evaluate the influence on prognosis. A total of 1,357 patients who underwent thyroid surgery for PTC were included. The clinicopathological characteristics were identified. Patients who underwent total thyroidectomy (n= 597) were studied to evaluate the influence of coexistent CLT on prognosis. Among the total 1,357 patients, 359 (26.5%) had coexistent CLT. In the CLT group, the prevalence of females was higher than in the control group without CLT (P< 0.001). Mean tumor size and mean age in the patients with CLT were smaller than without CLT (P= 0.040, P= 0.047, respectively). Extrathyroidal extension in the patients with CLT was significantly lower than without CLT (P= 0.016). Among the subset of 597 patients, disease-free survival rate in the patients with CLT was significantly higher than without CLT (P= 0.042). However, the multivariate analysis did not reveal a negative association between CLT coexistence and recurrence. Patients with CLT display a greater female preponderance, smaller size, younger and lower extrathyroidal extension. CLT is not a significant independent negative predictive factor for recurrence, although presence of CLT indicates a reduced risk of recurrence.
学术搜索中的文章
JS Jeong, HK Kim, CR Lee, S Park, JH Park, SW Kang… - Journal of Korean medical science, 2012