作者
Nicolas Sayegh, Umang Swami, Yeonjung Jo, Georges Gebrael, Benjamin Haaland, Shilpa Gupta, Melissa Plets, Maha HA Hussain, David I Quinn, Primo N Lara, Ian M Thompson, Neeraj Agarwal
发表日期
2023/8/1
期刊
JAMA network open
卷号
6
期号
8
页码范围
e2326546-e2326546
出版商
American Medical Association
简介
Importance
Black patients present with more aggressive disease and experience higher mortality than White patients with prostate cancer. Race and social determinants of health influence prostate cancer-specific mortality and overall survival (OS); however, in a previous trial, Black patients did not have inferior outcomes compared with White patients, possibly because of equitable access to care available in a clinical trial setting.
Objective
To compare differences in survival outcomes of patients with metastatic castration-sensitive prostate cancer (mCSPC) by race in a phase 3 trial with a large proportion of Black patients.
Design, Setting, and Participants
This secondary analysis of patient-level data of a prospective phase 3 randomized clinical trial included patients with newly diagnosed mCSPC enrolled between March 1, 2013, and July 15, 2017. Analysis was conducted between December 2022 and February 2023 …
学术搜索中的文章
N Sayegh, U Swami, Y Jo, G Gebrael, B Haaland… - JAMA network open, 2023