作者
Vinay Mathew Thomas, Yeonjung Jo, Nishita Tripathi, Soumyajit Roy, Beverly Chigarira, Arshit Narang, Georges Gebrael, Chadi Hage Chehade, Nicolas Sayegh, Gliceida Galarza Fortuna, Richard Ji, Patrick Campbell, Haoran Li, Neeraj Agarwal, Sumati Gupta, Umang Swami
发表日期
2024/5/1
期刊
JAMA Network Open
卷号
7
期号
5
页码范围
e249417-e249417
出版商
American Medical Association
简介
Importance
The treatment paradigm for advanced urothelial carcinoma (aUC) has undergone substantial transformation due to the introduction of effective, novel therapeutic agents. However, outcomes remain poor, and little is known about current treatment approaches and attrition rates for patients with aUC.
Objectives
To delineate evolving treatment patterns and attrition rates in patients with aUC using a US-based patient-level sample.
Design, Setting, and Participants
This retrospective cohort study used patient-level data from the nationwide deidentified electronic health record database Flatiron Health, originating from approximately 280 oncology clinics across the US. Patients included in the analysis received treatment for metastatic or local aUC at a participating site from January 1, 2011, to January 31, 2023. Patients receiving treatment for 2 or more different types of cancer or participating in clinical trials were …
学术搜索中的文章
VM Thomas, Y Jo, N Tripathi, S Roy, B Chigarira… - JAMA Network Open, 2024