作者
Mario Fioravanti, Taku Nakashima, Jun Xu, Amit Garg
发表日期
2014/7/1
来源
BMJ open
卷号
4
期号
7
页码范围
e005090
出版商
British Medical Journal Publishing Group
简介
Objective
To evaluate the safety profile of nicergoline compared with placebo and other active agents from published randomised controlled trials.
Design
Systematic review and meta-analysis of nicergoline compared with placebo and other active agents across various indications.
Data sources
MEDLINE, Medline-in-process, Cochrane, EMBASE, EMBASE alerts, Cochrane Central Register of Controlled Trials (CENTRAL), Cochrane Database of Systematic Reviews (CDSR) and Cochrane Methodology Register (CMR) for all the randomised controlled trials, open-label or blinded, in adults treated with nicergoline. Studies published until August 2013 were included.
Review method
29 studies were included for data extraction. The studies included in this review were majorly from European countries and mostly in cerebrovascular disease (n=15) and dementia (n=8).
Results
The treatment withdrawals were …
学术搜索中的文章
M Fioravanti, T Nakashima, J Xu, A Garg - BMJ open, 2014