作者
Peter A McCullough, Claudine T Jurkovitz, Pablo E Pergola, Janet B McGill, Wendy W Brown, Alan J Collins, Shu-Cheng Chen, Suying Li, Ajay Singh, Keith C Norris, Michael J Klag, George L Bakris, KEEP Investigators
发表日期
2007/6/11
期刊
Archives of Internal Medicine
卷号
167
期号
11
页码范围
1122-1129
出版商
American Medical Association
简介
Background
The relationships of anemia, microalbuminuria, and estimated glomerular filtration rate (eGFR) with cardiovascular disease (CVD) and subsequent death are not fully understood. We hypothesized that each of these chronic kidney disease–related measures would have an independent relationship with CVD.
Methods
A cohort of 37 153 persons screened in the National Kidney Foundation's Kidney Early Evaluation Program were followed up for a median of 16.0 months (range, 0.2-47.5 months). Participants were volunteers who completed surveys regarding past medical events and who underwent blood pressure and laboratory testing. Estimated glomerular filtration rate was computed using a 4-variable equation. Mortality was ascertained by linkage to national data systems.
Results
Of 37 153 persons, the mean ± SD age was 52.9 ± 15.9 years, and 68.7% were female. A total of 1835 (4.9%) had a self …
引用总数
学术搜索中的文章
PA McCullough, CT Jurkovitz, PE Pergola, JB McGill… - Archives of Internal Medicine, 2007