作者
Richard Castillo, Ngoc Pham, Sobiya Ansari, Dmitriy Meshkov, Sarah Castillo, Min Li, Adenike Olanrewaju, Brian Hobbs, Edward Castillo, Thomas Guerrero
发表日期
2014/12
期刊
Radiation Oncology
卷号
9
页码范围
1-10
出版商
BioMed Central
简介
Background
A retrospective analysis is performed to determine if pre-treatment [18 F]-2-fluoro-2-deoxyglucose positron emission tomography/computed tomography (FDG PET/CT) image derived parameters can predict radiation pneumonitis (RP) clinical symptoms in lung cancer patients.
Methods and Materials
We retrospectively studied 100 non-small cell lung cancer (NSCLC) patients who underwent FDG PET/CT imaging before initiation of radiotherapy (RT). Pneumonitis symptoms were evaluated using the Common Terminology Criteria for Adverse Events version 4.0 (CTCAEv4) from the consensus of 5 clinicians. Using the cumulative distribution of pre-treatment standard uptake values (SUV) within the lungs, the 80th to 95th percentile SUV values (SUV80 to SUV95) were determined. The effect of pre-RT FDG uptake, dose, patient and treatment …
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R Castillo, N Pham, S Ansari, D Meshkov, S Castillo… - Radiation Oncology, 2014