作者
Tom T Karnezis, Andrew B Baker, Zachary M Soler, Sarah K Wise, Shruthi K Rereddy, Zara M Patel, Nelson M Oyesiku, John M DelGaudio, Constantinos G Hadjipanayis, Bradford A Woodworth, Kristen O Riley, John Lee, Michael D Cusimano, Satish Govindaraj, Alkis Psaltis, Peter John Wormald, Steve Santoreneos, Raj Sindwani, Samuel Trosman, Janalee K Stokken, Troy D Woodard, Pablo F Recinos, W Alexander Vandergrift III, Rodney J Schlosser
发表日期
2016/11
期刊
International forum of allergy & rhinology
卷号
6
期号
11
页码范围
1117-1125
简介
Background
In patients undergoing transnasal endoscopic sellar surgery, an analysis of risk factors and predictors of intraoperative and postoperative cerebrospinal fluid leak (CSF) would provide important prognostic information.
Methods
A retrospective review of patients undergoing endoscopic sellar surgery for pituitary adenomas or craniopharyngiomas between 2002 and 2014 at 7 international centers was performed. Demographic, comorbidity, and tumor characteristics were evaluated to determine the associations between intraoperative and postoperative CSF leaks. Correlations between reconstructive and CSF diversion techniques were associated with postoperative CSF leak rates. Odds ratios (OR) were identified using a multivariate logistic regression model.
Results
Data were collected on 1108 pituitary adenomas and 53 craniopharyngiomas. Overall, 30.1% of patients had an intraoperative leak …
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TT Karnezis, AB Baker, ZM Soler, SK Wise… - International forum of allergy & rhinology, 2016