作者
Phillip S Cuculich, Junjie Zhang, Yong Wang, Kavit A Desouza, Ramya Vijayakumar, Pamela K Woodard, Yoram Rudy
发表日期
2011/10/25
期刊
Journal of the American College of Cardiology
卷号
58
期号
18
页码范围
1893-1902
出版商
American College of Cardiology Foundation
简介
Objectives
The aim of this study was to noninvasively image the electrophysiological (EP) substrate of human ventricles after myocardial infarction and define its characteristics.
Background
Ventricular infarct border zone is characterized by abnormal cellular electrophysiology and altered structural architecture and is a key contributor to arrhythmogenesis. The ability to noninvasively image its electrical characteristics could contribute to understanding of mechanisms and to risk-stratification for ventricular arrhythmia.
Methods
Electrocardiographic imaging, a noninvasive functional EP imaging modality, was performed during sinus rhythm (SR) in 24 subjects with infarct-related myocardial scar. The abnormal EP substrate on the epicardial aspect of the scar was identified, and its location, size, and morphology were compared with the anatomic scar imaged by other noninvasive modalities.
Results
Electrocardiographic …
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PS Cuculich, J Zhang, Y Wang, KA Desouza… - Journal of the American College of Cardiology, 2011