作者
Aaron D Baugh, Stephen Shiboski, Nadia N Hansel, Victor Ortega, Igor Barjaktarevic, R Graham Barr, Russell Bowler, Alejandro P Comellas, Christopher B Cooper, David Couper, Gerard Criner, Jeffrey L Curtis, Mark Dransfield, Chinedu Ejike, MeiLan K Han, Eric Hoffman, Jamuna Krishnan, Jerry A Krishnan, David Mannino, Robert Paine III, Trisha Parekh, Stephen Peters, Nirupama Putcha, Stephen Rennard, Neeta Thakur, Prescott G Woodruff
发表日期
2022/4/1
期刊
American journal of respiratory and critical care medicine
卷号
205
期号
7
页码范围
819-829
出版商
American Thoracic Society
简介
Rationale: African American individuals have worse outcomes in chronic obstructive pulmonary disease (COPD).
Objectives: To assess whether race-specific approaches for estimating lung function contribute to racial inequities by failing to recognize pathological decrements and considering them normal.
Methods: In a cohort with and at risk for COPD, we assessed whether lung function prediction equations applied in a race-specific versus universal manner better modeled the relationship between FEV1, FVC, and other COPD outcomes, including the COPD Assessment Test, St. George’s Respiratory Questionnaire, computed tomography percent emphysema, airway wall thickness, and 6-minute-walk test. We related these outcomes to differences in FEV1 using multiple linear regression and compared predictive performance between fitted models using root mean squared error and Alpaydin’s paired F test …
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AD Baugh, S Shiboski, NN Hansel, V Ortega… - American journal of respiratory and critical care …, 2022