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Data on malaria transmission intensity and prevalences of asexual parasites and of gametocytes were obtained in an urban district of Yaounde, Cameroon. The transmission level from mosquito to human was determined by indoor night capture of mosquitoes on human volunteers, revealing a calculated entomological inoculation rate of 34 infectious bites per person per year. Only Anopheles gambiae and A. funestus contributed to malaria transmission and their distribution was seasonal. Cross-sectional surveys every 2 months from July 1999 to May 2000 (n = 965) showed average annual prevalences of 35% Plasmodium falciparum asexual parasites (range 29–38%) and 4.4% gametocytes (range 0–6.7%). Prevalence of high parasitaemia (> 400 parasites/μL) and of gametocytes was seasonal. Prevalence of asexual parasitaemias and of gametocytaemias was age-dependent. The potential infectious …