作者
Morgan R Pokorny, Maarten De Rooij, Earl Duncan, Fritz H Schröder, Robert Parkinson, Jelle O Barentsz, Leslie C Thompson
发表日期
2014/7/1
期刊
European urology
卷号
66
期号
1
页码范围
22-29
出版商
Elsevier
简介
Background
The current diagnosis of prostate cancer (PCa) uses transrectal ultrasound–guided biopsy (TRUSGB). TRUSGB leads to sampling errors causing delayed diagnosis, overdetection of indolent PCa, and misclassification. Advances in multiparametric magnetic resonance imaging (mpMRI) suggest that imaging and selective magnetic resonance (MR)–guided biopsy (MRGB) may be superior to TRUSGB.
Objective
To compare the diagnostic efficacy of the magnetic resonance imaging (MRI) pathway with TRUSGB.
Design, setting, and participants
A total of 223 consecutive biopsy-naive men referred to a urologist with elevated prostate-specific antigen participated in a single-institution, prospective, investigator-blinded, diagnostic study from July 2012 through January 2013.
Intervention
All participants had mpMRI and TRUSGB. Men with equivocal or suspicious lesions on mpMRI also underwent MRGB …
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MR Pokorny, M De Rooij, E Duncan, FH Schröder… - European urology, 2014