作者
Arjun Rohit Adapa, Joseph Raynor Linzey, Badih Junior Daou, Unnati Vikram Mehta, Twisha Patel, Sreelatha Ponnaluri-Wears, Laraine Lynn Washer, B Gregory Thompson, Paul Park, Aditya Swarup Pandey
发表日期
2021/1/1
期刊
Clinical Neurology and Neurosurgery
卷号
200
页码范围
106353
出版商
Elsevier
简介
Objective
Surgical site infection (SSI) in neurosurgical patients increases morbidity. Despite the rise of methicillin-resistant Staphylococcus aureus (MRSA) colonization, there is little consensus regarding antibiotic prophylaxis for SSI in MRSA-colonized neurosurgical patients. Our objective was to examine the incidence of SSI in MRSA-colonized neurosurgical patients and interrogate whether MRSA-specific antibiotic prophylaxis reduces SSIs.
Methods
We performed a retrospective analysis of adult patients undergoing neurosurgical procedures between 2013 and 2018. The primary outcome was SSI in patients with MRSA colonization receiving MRSA-specific antibiotics. Secondary outcomes included predictors of SSI, including whether broad use of MRSA-specific antibiotics affects SSI rate.
Results
Of 9739 procedures, 376 had SSI (3.9 %). Seven hundred forty-four procedures (7.6 %) were performed on patients …
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AR Adapa, JR Linzey, BJ Daou, UV Mehta, T Patel… - Clinical Neurology and Neurosurgery, 2021