作者
Bob Roozenbeek, Hester F Lingsma, Fiona E Lecky, Juan Lu, James Weir, Isabella Butcher, Gillian S McHugh, Gordon D Murray, Pablo Perel, Andrew I Maas, Ewout W Steyerberg
发表日期
2012/5/1
期刊
Critical care medicine
卷号
40
期号
5
页码范围
1609-1617
出版商
LWW
简介
Objective:
The International Mission on Prognosis and Analysis of Clinical Trials and Corticoid Randomisation After Significant Head injury prognostic models predict outcome after traumatic brain injury but have not been compared in large datasets. The objective of this is study is to validate externally and compare the International Mission on Prognosis and Analysis of Clinical Trials and Corticoid Randomisation after Significant Head injury prognostic models for prediction of outcome after moderate or severe traumatic brain injury.
Design:
External validation study.
Patients:
We considered five new datasets with a total of 9,036 patients, comprising three randomized trials and two observational series, containing prospectively collected individual traumatic brain injury patient data.
Measurements and Main Results:
Outcomes were mortality and unfavorable outcome, based on the Glasgow Outcome Score at 6 months …
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B Roozenbeek, HF Lingsma, FE Lecky, J Lu, J Weir… - Critical care medicine, 2012