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Six new 3ß, 5a, 6p-trihydroxylated sterols 21-26 have been isolatedfrom the spongesHippospongia communis, Spongia officinalis, and Ircinia variabilis, along with the previously reported triols 12-20. Eleven 3 ß, 6a-dihydroxylated sterols 1—11, isolatedfrom the sponge Spongionella gracilis, are also reported. Of these sterols nine are new [3-11]. The structures of the new natural polyols were determined by spectral data. A partial synthesis of diol 6 confirmed the structure assignment.