作者
Katharina Brosch, Vincent Hammes, Paula Usemann, Frederike Stein, Florian Thomas-Odenthal, Lea Teutenberg, Janik Goltermann, Susanne Meinert, Kira Flinkenflügel, Alexandra Winter, Katharina Thiel, Tim Hahn, Nils Winter, Elvisha Dhamala, Axel Krug, Udo Dannlowski, Igor Nenadić, Andreas Jansen, Tilo Kircher, Nina Alexander
发表日期
2024/5/15
期刊
Biological Psychiatry
卷号
95
期号
10
页码范围
S178-S179
出版商
Elsevier
简介
Background
Individuals who experienced childhood sexual abuse (CSA) are characterized by higher general trauma load and worse health outcomes compared to other types of maltreatment. CSA-specific effects on brain morphometry have been previously described, however, these findings are limited by methodological issues and small sample sizes. In this study, to reliably identify unique effects of CSA on the brain, we compared sexually abused individuals to non-sexually abused individuals who were matched regarding trauma load.
Methods
We investigated n= 195 individuals with CSA and selected a 1: 1 matched sample of non-sexually maltreated individuals, matched for age, sex, diagnostic group and trauma load. The sample included men and women aged 18-65 with and without current or previous diagnosis of depression. We investigated brain structural differences in gray matter volume (GMV) and …
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K Brosch, V Hammes, P Usemann, F Stein… - Biological Psychiatry, 2024