作者
Ivan M Rosado-Mendez, Mark L Palmeri, Lindsey C Drehfal, Quinton W Guerrero, Heather Simmons, Helen Feltovich, Timothy J Hall
发表日期
2017/4/1
期刊
Ultrasound in medicine & biology
卷号
43
期号
4
页码范围
790-803
出版商
Elsevier
简介
Shear wave elasticity imaging has shown promise in evaluation of the pregnant cervix. Changes in shear wave group velocity have been attributed exclusively to changes in stiffness. This assumes homogeneity within the region of interest and purely elastic tissue behavior. However, the cervix is structurally/microstructurally heterogeneous and viscoelastic. We therefore developed strategies to investigate these complex tissue properties. Shear wave elasticity imaging was performed ex vivo on 14 unripened and 13 misoprostol-ripened cervix specimens from rhesus macaques. After tests of significant and uniform shear wave displacement, as well as reliability of estimates, group velocity decreased significantly from the distal (vaginal) to proximal (uterine) end of unripened, but not ripened, specimens. Viscosity was quantified by the slope of the phase velocity versus frequency. Dispersion was observed in both …
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