作者
Nesrin Ercelen, Sibel Mercan
发表日期
2005
来源
Medicine
卷号
1
页码范围
155-164
简介
Achievements in gene mapping and the development of sophisticated statistical methods have enabled scientists to make great progress in the identification of genes. With at least 30.000 genes in the human genome waiting to be identified and characterized, the challenge now is to dissect complex genetic disorders such as obesity, diabetes, cancer and neurodegenerative diseases. Most researchers believe that complex disorders result from a large number of genetic variants, each making small contributions. Still others have proposed that these disorders result from an interaction between one or more genetic variants and non genetic disease risk factors. Understanding the genetic background of diseases might enable us to provide potential targets for effective treatment, screening and prevention. It will also be the beginning of personalized medicine since it will enable us to understand the genetic basis of why …
引用总数
学术搜索中的文章