作者
Allison Weinkle, Cory Pettit, Aditi Jani, Jesse Keller, Yuanyuan Lu, Stephen Malachowski, John C Trinidad, Benjamin H Kaffenberger, Elizabeth N Ergen, Lauren C Hughey, David Smith, Lucia Seminario-Vidal
发表日期
2019/9/1
期刊
Journal of the American Academy of Dermatology
卷号
81
期号
3
页码范围
749-757
出版商
Mosby
简介
Background
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening conditions that may present with similar findings to other severe dermatologic diseases.
Objective
The primary objective of this exploratory study was to explore factors associated with SJS/TEN and develop a model that provides the predicted probability of SJS/TEN for patients for whom the diagnosis of SJS/TEN is considered.
Methods
Retrospective review of consultations for patients with suspected SJS, TEN, or overlap at 4 academic dermatology consultation services.
Results
Overall, 208 patients were included; 59 (28.4%) had a final diagnosis of SJS/TEN, and 149 (71.6%) were given a different diagnosis. The most common mimickers were drug hypersensitivity syndrome (n = 21, 10.1%), morbilliform drug eruption (n = 18, 8.7%), erythema multiforme (n = 15, 7.2%), and acute generalized exanthematous …
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A Weinkle, C Pettit, A Jani, J Keller, Y Lu… - Journal of the American Academy of Dermatology, 2019