作者
Safi U Khan, Mohammed Osman, Muhammad U Khan, Muhammad Shahzeb Khan, Di Zhao, Mamas A Mamas, Nazir Savji, Ahmad Al-Abdouh, Rani K Hasan, Erin D Michos
发表日期
2020/4/7
来源
Annals of internal medicine
卷号
172
期号
7
页码范围
474-483
出版商
American College of Physicians
简介
Background
The safety and effectiveness of dual therapy (direct oral anticoagulant [DOAC] plus P2Y12 inhibitor) versus triple therapy (vitamin K antagonist plus aspirin and P2Y12 inhibitor) in patients with nonvalvular atrial fibrillation (AF) after percutaneous coronary intervention (PCI) is unclear.
Purpose
To examine the effects of dual versus triple therapy on bleeding and ischemic outcomes in adults with AF after PCI.
Data Sources
Searches of PubMed, EMBASE, and the Cochrane Library (inception to 31 December 2019) and ClinicalTrials.gov (7 January 2020) without language restrictions; journal Web sites; and reference lists.
Study Selection
Randomized controlled trials that compared the effects of dual versus triple therapy on bleeding, mortality, and ischemic events in adults with AF after PCI …
学术搜索中的文章
SU Khan, M Osman, MU Khan, MS Khan, D Zhao… - Annals of internal medicine, 2020