作者
Sylvester Dodzi Nyadanu, Gizachew A Tessema, Ben Mullins, Kevin Chai, Maayan Yitshak-Sade, Gavin Pereira
发表日期
2023/12/27
期刊
Environmental Health Perspectives
卷号
131
期号
12
页码范围
127017
简介
Background
There is limited and inconsistent evidence on the risk of ambient temperature on small for gestational age (SGA) and there are no known related studies for large for gestational age (LGA). In addition, previous studies used temperature rather than a biothermal metric.
Objectives
Our aim was to examine the associations and critical susceptible windows of maternal exposure to a biothermal metric [Universal Thermal Climate Index (UTCI)] and the hazards of SGA and LGA.
Methods
We linked 385,337 singleton term births between 1 January 2000 and 31 December 2015 in Western Australia to daily spatiotemporal UTCI. Distributed lag nonlinear models with Cox regression and multiple models were used to investigate maternal exposure to UTCI from 12 weeks preconception to birth and the adjusted hazard ratios (HRs) of SGA and LGA.
Results
Relative to the median exposure, weekly and monthly specific exposures …
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