作者
Marlon Perera, Ghalib Jibara, Amy L Tin, Samuel Haywood, Daniel D Sjoberg, Nicole E Benfante, Sigrid V Carlsson, James A Eastham, Vincent Laudone, Karim A Touijer, Samson Fine, Peter T Scardino, Andrew J Vickers, Behfar Ehdaie
发表日期
2023/7/1
期刊
European Urology Focus
卷号
9
期号
4
页码范围
662-668
出版商
Elsevier
简介
Background
Active surveillance (AS) is recommended as the preferred treatment for men with low-risk disease. In order to optimize risk stratification and exclude undiagnosed higher-grade disease, most AS protocols recommend a confirmatory biopsy.
Objective
We aimed to compare outcomes among men with grade group (GG) 2/3 prostate cancer on initial biopsy with those among men whose disease was initially GG1 but was upgraded to GG2/3 on confirmatory biopsy.
Design, setting, and participants
We reviewed patients undergoing radical prostatectomy (RP) in two cohorts: “immediate RP group,” with GG2/3 cancer on diagnostic biopsy, and “AS group,” with GG1 cancer on initial biopsy that was upgraded to GG2/3 on confirmatory biopsy.
Outcome measurements and statistical analysis
Probabilities of biochemical recurrence (BCR) and salvage therapy were determined using multivariable Cox regression …
学术搜索中的文章
M Perera, G Jibara, AL Tin, S Haywood, DD Sjoberg… - European Urology Focus, 2023