作者
Behfar Ehdaie, Thomas F Chromecki, Richard K Lee, Yair Lotan, Vitaly Margulis, Pierre I Karakiewicz, Giacomo Novara, Jay D Raman, Casey Ng, William T Lowrance, Douglas S Scherr, Shahrokh F Shariat
发表日期
2011/7/1
期刊
The Journal of urology
卷号
186
期号
1
页码范围
66-72
出版商
No longer published by Elsevier
简介
PURPOSE
The relationship between body mass index and urothelial carcinoma is poorly understood. We investigated the association between body mass index and oncological outcomes in patients with upper tract urothelial carcinoma.
MATERIALS AND METHODS
We retrospectively reviewed the records of 520 patients treated with radical nephroureterectomy for upper tract urothelial carcinoma. Univariate Cox regression analysis was done to evaluate estimated recurrence-free, cancer specific and overall survival. We created a multivariate model based on preoperative and postoperative characteristics.
RESULTS
Median patient body mass index was 27.9 kg/m2 (IQR 6.7). Patients with a higher body mass index were more likely to have infiltrative architecture (p <0.001) and lymphovascular invasion (p = 0.012). In the preoperative model body mass index 25 to 29 (HR 2.25, 95% CI 1.3–3.8, p = 0.003) and 30 kg …
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B Ehdaie, TF Chromecki, RK Lee, Y Lotan, V Margulis… - The Journal of urology, 2011