作者
Michael Rink, Behfar Ehdaie, Eugene K Cha, David A Green, Pierre I Karakiewicz, Marko Babjuk, Vitaly Margulis, Jay D Raman, Robert S Svatek, Harun Fajkovic, Richard K Lee, Giacomo Novara, Jens Hansen, Siamak Daneshmand, Yair Lotan, Wassim Kassouf, Hans-Martin Fritsche, Armin Pycha, Margit Fisch, Douglas S Scherr, Shahrokh F Shariat, Bladder Cancer Research Consortium
发表日期
2012/10/1
期刊
European urology
卷号
62
期号
4
页码范围
677-684
出版商
Elsevier
简介
BACKGROUND: Dissimilarities in management and outcomes exist between upper tract urothelial carcinoma (UTUC) and urothelial carcinoma of the bladder (UCB). OBJECTIVE: The aim of this study was to analyze the stage-specific impact of upper or lower urinary tract tumor location on oncologic outcomes. DESIGN, SETTING, AND PARTICIPANTS: Data were collected from 4335 patients with UCB treated with radical cystectomy (RC) and bilateral pelvic lymphadenectomy (PLND), 877 patients with ureteral UTUC, and 1615 with pelvicalyceal UTUC treated with radical nephroureterectomy (RNU). No patient received preoperative chemotherapy or radiation therapy. INTERVENTIONS: Patients were treated with RC and bilateral PLND or RNU. MEASUREMENTS: Outcomes were assessed according to primary tumor location. RESULTS AND LIMITATIONS: Compared to UTUC patients, UCB patients had more …
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M Rink, B Ehdaie, EK Cha, DA Green, PI Karakiewicz… - European urology, 2012