作者
J Steinbrink, M Kohl, Hellmuth Obrig, G Curio, F Syre, F Thomas, H Wabnitz, H Rinneberg, Arno Villringer
发表日期
2000/9/15
期刊
Neuroscience letters
卷号
291
期号
2
页码范围
105-108
出版商
Elsevier
简介
This work is the first to report optical intensity changes (ΔI/I ≈0.05%) with a latency between 60 and 160ms after electrical median nerve stimulation at 5Hz detected non-invasively through the intact adult human skull in volunteers. The signal is localised and reproducible when measuring at the same position on successive examinations. Compared to previous reports of fast optical changes in the human adult by a single group (Psychophysiology, 32 (1995) 505) the here reported changes are much smaller. They are in line with results from a photon transport calculation on a head model employing data from exposed cortical tissue. The origin of the signal found here is still unclear, however, they might be the non-invasive equivalent to the scattering changes found in exposed cortical tissue studies (J. Neurophysiol., 78 (1997) 1707).
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