作者
Qiushui He, Matti K Viljanen, Heikki Arvilommi, Birgitta Aittanen, Jussi Mertsola
发表日期
1998/8/19
期刊
Jama
卷号
280
期号
7
页码范围
635-637
出版商
American Medical Association
简介
Context
The prevalence of Bordetella pertussis and Bordetella parapertussis infections among outpatients in an immunized population is not known.
Objective
To study the prevalence of these infections in outpatients with paroxysmal cough in Finland, where the pertussis vaccine coverage of 4 doses is 98%.
Design
Prospective cohort study.
Setting
Thirty-two health centers in southwestern Finland.
Patients
A total of 584 patients with paroxysmal cough seen at local health centers from October 1994 through March 1997 from whom nasopharyngeal swabs were collected.
Main Outcome Measures
Prevalence of positive cultures for B pertussis or B parapertussis and/or positive polymerase chain reaction (PCR) results and frequency of symptoms in those with pertussis and parapertussis.
Results
A total of 153 subjects (26.2%) had Bordetella infection by culture or PCR: 93 (60.8%) had B pertussis infection, 49 (32.0%) had B …
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Q He, MK Viljanen, H Arvilommi, B Aittanen, J Mertsola - Jama, 1998