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A fatal case of 1,4butanediol (1,4BD) oral ingestion is reported here, in which a 51yearold man was found dead in his bed. According to the police report, the deceased was a known drug user. A glass bottle labeled (and later confirmed to be) “Butandiol 1,4” (1,4BD) was found in the kitchen. Furthermore, the deceased's friend stated that he consumed 1,4BD on a regular basis. The autopsy and histological examination of postmortem parenchymatous organ specimens did not revealed a clear cause of death. Chemicaltoxicological investigations revealed gammahydroxybutyrat (GHB) in body fluids and tissues in the following quantities: femoral blood 390 mg/L, heart blood 420 mg/L, cerebrospinal fluid 420 mg/L, vitreous humor 640 mg/L, urine 1600 mg/L, and head hair 26.7 ng/mg. In addition, 1,4BD was qualitatively detected in the head hair, urine, stomach contents, and the bottle. No other …