作者
Magdalena Kozela, Martin Bobak, Agnieszka Besala, Agnieszka Micek, Ruzena Kubinova, Sofia Malyutina, Diana Denisova, Marcus Richards, Hynek Pikhart, Anne Peasey, Michael Marmot, Andrzej Pająk
发表日期
2016/11/1
来源
European journal of preventive cardiology
卷号
23
期号
17
页码范围
1839-1847
出版商
Oxford University Press
简介
Background
Studies in western populations have shown a positive association between depression and cardiovascular disease (CVD) and all-cause mortality. The association with depressive symptoms seems to be graded, rather than limited to the presence versus the absence of depression. Evidence from populations with potentially different patterns of confounders helps to address the consistency of these findings. The objective of the study was to investigate the association between depressive symptoms and all-cause and CVD mortality in populations of Central and Eastern Europe.
Study design
This was a prospective cohort study.
Methods
A total of 24,542 participants aged 45–69 years, randomly selected from populations of Novosibirsk (Russia), Krakow (Poland) and six Czech towns, were included. Depressive symptoms, assessed by the 20-item …
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