作者
Emanuele Valeriani, Francesco Paciullo, Angelo Porfidia, Pasquale Pignatelli, Matteo Candeloro, Marcello Di Nisio, Marco Paolo Donadini, Claudio Maria Mastroianni, Roberto Pola, Paolo Gresele, Walter Ageno
发表日期
2023/2/1
来源
Journal of Thrombosis and Haemostasis
卷号
21
期号
2
页码范围
284-293
出版商
Elsevier
简介
Background
Retinal vein occlusion (RVO) represents a common thrombotic disorder.
Objectives
In this meta-analysis, we evaluated the efficacy and safety of anticoagulant and antiplatelet therapy in RVO.
Methods
MEDLINE and EMBASE were searched up to December 2021 for observational studies and randomized controlled trials including patients with RVO. Efficacy outcomes were best-corrected visual acuity improvement, recurrent RVO, fluorescein angiography improvement, cardiovascular events, and safety outcomes were major bleeding and intraocular bleeding.
Results
A total of 1422 patients (15 studies) were included. Antiplatelet therapy was administered to 477 patients (13 studies), anticoagulant therapy to 312 patients (12 studies), and 609 (7 studies) patients received no antithrombotic treatment. The treatment duration ranged between 0.5 and 3 months. The median follow-up duration was 12 months …
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E Valeriani, F Paciullo, A Porfidia, P Pignatelli… - Journal of Thrombosis and Haemostasis, 2023