作者
Adriano R Tonelli, Scott Johnson, Laith Alkukhun, Ruchi Yadav, Raed A Dweik
发表日期
2017/11
期刊
Respirology
卷号
22
期号
8
页码范围
1649-1655
出版商
John Wiley & Sons, Ltd
简介
Background and objective
A dilated pulmonary artery (PA) is a common finding in patients with pulmonary arterial hypertension (PAH). Little is known on the variations in PA size over time and whether these changes track with disease severity and/or predict long‐term survival.
Methods
We included patients with PAH who had at least two computed tomography (CT) scans of the chest done on different visits. Both scans matched the use of i.v. contrast.
Results
Pairs of CT scans were compared in 113 PAH patients. During a median (interquartile range (IQR)) time difference between scans of 8 (IQR: 3.5–20.0) months, we noted an increase in main PA diameter of 0.5 ± 1.8 mm (mean ± SD) (P = 0.008). When CT scans were performed >12 months apart (n = 47), the main PA diameter increased or decreased by >1 mm in 40% and 13% of the patients, respectively. An increase in main PA diameter was …
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