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The purpose is to provide a comprehensive report describing the clinical and imaging features of Coronavirus disease 2019 (COVID‐19)‐related acute invasive fungal sinusitis (AIFS) and associated comorbidities.

A retrospective study was conducted on 25 patients (12 males and 13 females, mean age of 53.9±9.1 years). All patients had positive polymerase chain reaction test for COVID‐19 and histopathological proof of AIFS. Patients underwent computed tomography (CT) and magnetic resonance examinations to assess sinonasal, orbital, and cranial spread.

The most prevalent comorbidity among the study cohort was diabetes mellitus (DM). Twenty‐one patients (84%) were diagnosed in the post‐COVID‐19 period after hospital discharge, with a mean interval of 19.1±9.2 days. Steroid treatment was given to 19 patients (76%). Orbital manifestations were the …