作者
H Wang, W Zi, Y Hao, D Yang, Z Shi, M Lin, S Wang, W Liu, Z Wang, X Liu, F Guo, Y Liu, G Xu, Y Xiong, X Liu, ACTUAL Investigators, Meng Zhang, Chengchun Liu, Yu Geng, Zongjie Shi, Jinhua Zhang, Hang Lin, Zhen Hu, Xiaorong Deng, Yue Wan, Jiandong Zhang, Mirui Qu, Zhiming Zhou, Xianjun Huang, Wei Wang, Haowen Xu, Tao Quan, Sheng Guan, Xiguang Tian, Lin Chen, Penghua Lv, Xiaobo Li, Shiquan Yang, Dan Wei, Shu Yang, Dequan Zheng, Xinyu Wu, Youfu Zeng, Mingyi Tu, Ping Jin, Yong Liu, Hua Li, Jiayang Fang, Guodong Xiao
发表日期
2017/7
期刊
European Journal of Neurology
卷号
24
期号
7
页码范围
935-943
简介
Background and purpose
Whether intravenous thrombolysis prior to endovascular treatment in patients with anterior circulation large‐vessel occlusion (LVO) is indispensable remains unclear. The aim was to retrospectively compare, in a Chinese population, the effectiveness and safety of direct endovascular treatment (DEVT) initiated within 4.5 h after onset with bridging therapy in acute anterior circulation LVO stroke patients.
Methods
A total of 363 patients, 160 in the bridging therapy group and 203 in the DEVT group, were enrolled between 2014 and 2016. Using propensity score matching analysis, 276 patients were matched. A modified Rankin Scale score of 0–2 was considered as good functional outcome.
Results
Good functional outcome at 90 days in the DEVT group [40.6% (56/138)] did not significantly differ from that in the bridging group [44.9% (62/138)] (P = 0.53). Rates of symptomatic intracranial …
学术搜索中的文章
H Wang, W Zi, Y Hao, D Yang, Z Shi, M Lin, S Wang… - European Journal of Neurology, 2017