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Global warming and salinization are inducing adverse effects on crop yield. Drought priming has been proved to improve drought tolerance of plants at later growth stages, however, whether and how drought priming at early growth stage alleviating salinity stress at later growth stage and improving water use efficiency (WUE) of plants remains unknown. Therefore, two wheat cultivars were subjected to drought priming at the 4th and 6th leaf stage and subsequent moderate salinity stress at 100 mmol NaCl applied at the later jointing growth stage. The growth, physiological responses, ABA signaling and WUE were investigated to unravel the regulating mechanisms of drought priming on subsequent salinity stress. The results showed that drought priming imposed at the early growth stage improved the leaf and root water potential while attenuated the ABA concentration in the leaves ([ABA]_leaf) for the primed …