作者
Brian R Lane, Paul Russo, Robert G Uzzo, Adrian V Hernandez, Stephen A Boorjian, R Houston Thompson, Amr F Fergany, Thomas E Love, Steven C Campbell
发表日期
2011/2
期刊
The Journal of urology
卷号
185
期号
2
页码范围
421-427
出版商
Wolters Kluwer
简介
Purpose
Factors that determine renal function after partial nephrectomy are not well- defined, including the impact of cold vs warm ischemia, and the relative importance of modifiable and nonmodifiable factors. We studied these determinants in a large cohort of patients with a solitary functioning kidney undergoing partial nephrectomy.
Materials and Methods
From 1980 to 2009, 660 partial nephrectomies were performed at 4 centers for tumor in a solitary functioning kidney under cold (300) or warm (360) ischemia. Data were collected in institutional review board approved registries and followup averaged 4.5 years. Preoperative and postoperative glomerular filtration rates were estimated via the Chronic Kidney Disease-Epidemiology Study equation.
Results
At 3 months after partial nephrectomy median glomerular filtration rate decreased by equivalent amounts with cold or warm ischemia (21% vs 22%, respectively …
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BR Lane, P Russo, RG Uzzo, AV Hernandez… - The Journal of urology, 2011