作者
Anant Mohan, V Kavitha, Karan Madan, Vijay Hadda, Randeep Guleria, GC Khilnani
发表日期
2016/9/1
来源
European Respiratory Journal
卷号
48
期号
suppl 60
出版商
European Respiratory Society
简介
Background: Fractional Exhaled Nitric Oxide (FeNO) is a promising non invasive tool for detecting airway inflammation; however, it9s utility in predicting asthma control is not well defined.
Aims and Objectives: The ability of serial measurements of FeNO in determining and predicting clinical control of asthma was investigated.
Methods: Steroid naïve asthmatics who were clinically eligible for receiving ICS were recruited and the following parameters were measured at inclusion and after 6 - 8 weeks of ICS treatment: FeNO (using Niox Mino point of care device), peak expiratory flow rate (PEFR) variability, asthma control test (ACT) score, forced expiratory volume in 1 sec (FEV1), and bronchodilator reversibility (BDR).
Results: 96 patients were recruited (61% males; mean (SD) age, 33.4 (12.8) years). The median FeNO levels at baseline and after therapy were 41.5 (25 - 66) and 35.5 (19 - 47) ppb respectively (p=0.01 …
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