作者
Albree Tower-Rader, Divyanshu Mohananey, Andrew To, Harry M Lever, Zoran B Popovic, Milind Y Desai
发表日期
2019/10
来源
JACC: Cardiovascular Imaging
卷号
12
期号
10
页码范围
1930-1942
出版商
American College of Cardiology Foundation
简介
Objectives
The association of left ventricular global longitudinal strain (LV-GLS) with clinical outcomes in patients with hypertrophic cardiomyopathy (HCM) has been examined in multiple studies. The authors conducted a systematic review aimed at summarizing and critically appraising the current evidence.
Background
HCM is a common genetic cardiovascular disease with an estimated prevalence of 1 in 500 patients. LV-GLS derived from speckle tracking echocardiography is a sensitive noninvasive method of assessing regional left ventricular function. Several studies have suggested association of abnormal LV-GLS with outcomes in HCM patients.
Methods
A computerized literature search of all English language publications in the PubMed and EMBASE databases was made looking at all randomized and nonrandomized studies conducted on patients with HCM where association of LV-GLS with clinical …
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